Mathew Leckie could win his first minutes of the season this weekend after shaking off an injury problem to get back out on the track for Hertha Berlin.
Meanwhile, there's another big Premier League test in store for Mathew Ryan, while fierce rivalries are set to play out across Europe.
Read on to find out when our Caltex Socceroos are in action!
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ALL KICK OFF TIMES AEST
Premier League: Seagulls circle wounded Spurs
Mathew Ryan's Brighton and Hove Albion will look to condemn Tottenham to a fourth straight defeat in all competitions when they meet at Amex Stadium on Sunday 2.30am
Aaron Mooy’s Huddersfield Town take their hunt for a first victory away to Leicester City on Sunday 12.00am.
England: Luongo leading QPR revival
Mile Jedinak and Aston Villa are at home to Sheffield Wednesday on Sunday 12.00am, while fellow midfielder Jackson Irvine travels to Reading with Hull City at the same time.
After a precious win against James Meredith’s Millwall on Thursday morning, Queens Park Rangers hope Massimo Luongo can carry on his scoring form against Norwich City at 2.30am on Sunday.
Millwall and Meredith travel to high-flying West Brom on Sunday 12.00am.
Bailey Wright’s Bristol City face a stern away test at Wigan Athletic on Saturday morning at 4.45am.
Germany: Leckie back for Berlin?
Mathew Leckie returned to Hertha Berlin training this week and is in line to feature against Borussia Monchengladbach on Saturday night at 11.30pm.
Robbie Kruse, who starred in Bochum's last ousting, is in action at the slightly earlier time of 9.00pm in 2. Bundesliga, away to Holstein Kiel.
Scotland: Celtic seek to kick on
Daniel Arzani, scorer of a splendid free-kick for Celtic's development side in midweek, will hope to join Tom Rogic in the squad to visit Kilmarnock on Sunday 9.30pm.
Celtic are coming off a precious late Europa League win over Rosenborg.
Elsewhere, Hibernian’s Mark Milligan and Jamie Maclaren are off to Dundee on Sunday 12.00am.
Ben Garuccio’s Hearts entertain Livingston at home at the same time.
Eredivisie: No easy rebound for PSV
After PSV's tough 4-0 loss to Barcelona in the UEFA Champions League, Trent Sainsbury and Aziz Behich may be called into defence for another giant clash with title rivals Ajax.
The two Dutch powerhouses face off on Monday 12.45am.
A week after taking on Ajax, Ajdin Hrustic and Gronigen now face off against Eredivisie heavyweights AZ Alkmaar on Sunday 10.30pm.
At the same time, Denis Genreau and PEC Zwolle face FC Emmen. John Iredale’s Heerenveen travel to Excelsior at 3.45am on Sunday.
Rest of Europe: Derby date for Degenek
Milos Degenek was impressive in keeping Napoli at bay on Wednesday morning and the big tasks aren't over there with Red Star Belgrade to take on Partizan Belgrade in the Eternal derby on Monday 3.00am.
Danny Vukovic’s Genk are on a high after accounting for Malmo in their UEFA Europa League opener; they now turn their attention towards an excursion to Cercle Brugge on Monday 4.00am.
Midtjylland closed to within a point of top spot by beating Copenhagen last time out. Awer Mabil’s side now face SonderjyskE on Sunday 8.00pm.
Also in Denmark, Mustafa Amini and AGF host Brondby on Monday 2.00am.
Elsewhere in Europe, Tomi Juric’s Luzern take on FC Zurich on Monday 12.00am, MSK Zilina and Aleksandar Susnjar face FK Senica on Sunday 3.00am, and Apostolos Giannou’s AEK Larnaca host AC Omonia on Tuesday 2.00am.
Asia: Crunch Kawasaki clash for Langerak
Mitchell Duke and Shimizu S-Pulse entertain Gamba Osaka in the J-League tonight at 8.30pm.
Also in Japan, Mitchell Langerak’s Nagoya Grampus travel to second-placed Kawasaki Frontale on Saturday at 8.00pm.
And in Saudi Arabia, Brad Jones’ Al Nassr welcome Al-Taawoun on Tuesday 3.10am, while Matt Jurman’s Al-Ittihad aren't in action until Thursday, against Al-Wehda at 1.55am.
Former Socceroos duo appointed as Wanderers W-League coaches
Former Caltex Socceroos duo Dean Heffernan and Michael Beauchamp have been appointed head coach and assistant coach of Western Sydney Wanderers' Westfield W-League side respectively... Heffernan, who made nine appearances for the men’s outfit during season 2013/14, replaces outg
Aussies Abroad: Mixed fortunes overnight for Ryan and Degenek
There were two Caltex Socceroos in action on Wednesday morning (AEST), with significant results playing out for Mat Ryan and Milos Degenek. Ryan’s Brighton & Hove Albion suffered an agonising late loss to Tottenham Hotspur in London, with an 88th-minute Christian Eriksen goal
Aussies Abroad: Two-year Danish Superliga record falls as Mabil's Midtjylland lose to Brondby
Awer Mabil’s hopes of clinching the Danish Superliga title with FC Midtjylland suffered a blow after a 2-1 loss to Brondby earlier this morning. Marc Dal Hende opened the scoring early for Midtjylland, but a swift equaliser from Simon Hedlund and a deflected winner from Jens M
Former Caltex Socceroos striker announces retirement
Former Caltex Socceroos forward and Adelaide United legend Bruce Djite has announced his retirement from football. Djite, 32, was most recently playing for Indonesian club PSM Makassar before returning to Australia last year. “I’ve had a few opportunities come up that inter