Two Caltex Socceroos could be set for their first competitive minutes of the season while a host of regulars are gearing up for the new campaign.
A big schedule of matches presents the perfect opportunity for our homegrown stars to press their claims for key roles.
Here's how the weekend is shaping up for our internationals.
AUSSIES ABROAD: Rogic, Jedinak and Mooy all in action
BACK TO THE GRIND
Danny Vukovic is one of three players in the frame for competitive action with his KRC Genk side visiting Lokeren in their Belgian Pro League opener early Monday morning (4:00am AEST).
The match falls in between the club's two Europa League second qualifying round matches against Luxembourg-based Fola Esch.
Vukovic will expect to take his place between the sticks after starting 38 matches as Genk finished fifth last term.
Milos Degenek has already sunk his teeth into the season, making an immediate impression at new club Red Star Belgrade.
The defender has recorded a hat-trick of clean sheets in his three starts to date and will hope to keep that run going in a Serbian SuperLiga encounter with Radnicki Nis at 3:00am (AEST) on Monday.
Meanwhile, in Switzerland, Tomi Juric may come into contention for FC Luzern's trip to FC Thun at midnight (AEST) on Sunday.
The 27-year-old missed the season-opening 2-0 loss to Neuchatel Xamax through injury.
Leagues across Europe are drawing closer to their first matchdays and several Caltex Socceroos will be looking to impress this weekend.
Among them is Mile Jedinak, with the midfielder likely to feature in Aston Villa's final pre-season engagement against Dynamo Dresden in Germany on Saturday (11:00pm AEST).
You can watch the match live on Villa's official YouTube channel.
Steve Bruce's side are warming up for their Championship opener against Jackson Irvine's Hull City, who are also in action on Saturday (midnight AEST) at League One side Barnsley.
Fellow midfielder Massimo Luongo should get another run when Queens Park Rangers host Union Berlin at 11:30pm on Saturday.
You can watch Luongo in action against the German outfit live online by purchasing a matchday pass from QPR.
Staying with German clubs, Jamie Maclaren will be eager to make the most of Darmstadt's clash with Roda JC on Saturday (10:00pm AEST).
Maclaren played 30 minutes in a draw with Aaron Mooy's Huddersfield Town last weekend and this could be the chance for him to push for a starting berth in the upcoming campaign.
Back in England and Mat Ryan's Brighton and Hove Albion meet Birmingham City at St Andrew's at midnight (AEST) on Saturday in what is the Seagulls' penultimate workout.
Elsewhere, Brad Jones' Feyenoord host Levante (Sunday 9:30pm AEST) less than a week out from their Super Cup clash with PSV.
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