Socceroos goalkeeper Mat Ryan returned to Valencia's starting line-up on Sunday, playing a full game in their 1-0 La Liga loss away to Sevilla.
But after the match, Valencia coach Nuno quit after just five wins in 13 league games this season.
Ryan had not played in La Liga since late August due to a knee injury.
Elsewhere in Europe, Mathew Leckie also made his return, playing 77 minutes in Ingolstadt's 4-0 Bundesliga loss to Hannover.
Robbie Kruse played 20 minutes as Stuttgart went down to Borussia Dortmund 4-1, while in Germany's second tier, James Holland completed a full shift in MSV Duisburg's victory and Ben Halloran came on in the 64th minute of Heidenheim's loss.
In the Dutch Eredivisie, Trent Sainsbury played a full game for PEC Zwolle, who lost 2-0 to Ajax, while Daniel De Silva also started for Roda JC in a 3-0 loss to Heerenveen.
Brent McGrath scored his seventh goal of the season but Fredericia lost in Denmark's second tier, while in the Superliga, Mustafa Amini came on for the last 16 minutes in Randers' 1-0 win over FC Nordsjaelland.
Jack Duncan sat on the bench for Randers, as did Aziz Behich for Bursaspor in Turkey.
Adam Federici came off with a foot injury at half-time of Bournemouth's 3-3 draw with Everton in the Premier League having conceded twice in the first half.
Mark Schwarzer sat on the bench as Jamie Vardy scored for a record-breaking 11th game in a row in Leicester City's 1-1 draw with Manchester United, while Mile Jedinak played 23 minutes in Crystal Palace's 5-1 win over Newcastle United.
In the Championship, Tommy Oar was the only man in action, coming on for the final few minutes of Ipswich Town's 3-0 win over Charlton.
Massimo Luongo (QPR), Jason Davidson (Huddersfield) and Neil Kilkenny (Preston North End) were benched by their respective clubs.
But in League One, both James Meredith (Bradford City) and Alex Cisak (Leyton Orient) played full matches.
Tom Rogic completed 61 minutes for Scottish Premiership leaders Celtic, as the Glasgow giants triumphed 3-1 at Inverness Caledonian Thistle.
Elsewhere, Scott McDonald notched an assist in Motherwell's 2-2 draw with Hearts before being subbed off in the 85th minute.
Jackson Irvine (Ross County) and Ryan McGowan (Dundee United) put in full shifts as both their teams lost, with Adam Taggart coming on late for Dundee United.
James Troisi teed up a goal in Al Ittihad's 3-2 loss to Al Khaleej in Saudi Arabia, while in United Arab Emirates, Mark Milligan completed 90 minutes as Baniyas lost and Brett Holman was taken off at the break in Emirates Club's defeat.
And Hyundai A-League teams can rest easy in the knowledge that they will not have to face Tim Cahill in the 2016 AFC Champions League after the Socceroo's Shanghai Shenhua side lost the Chinese FA Cup final 1-0 to Jiangsu Sainty on Sunday.
After a goalless first leg a week previously, the second leg took place at the Hongkou Stadium in Shanghai with the home side losing on pens.